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The centrally acting non-narcotic antitussive tipepidine produces antidepressant-like effect in the forced swimming test in rats
http://hdl.handle.net/2298/18938
http://hdl.handle.net/2298/18938a2ad42fe-ecf1-4ee9-bd67-7b3f1b03b783
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BBR_205_1_fig1-2.pdf (27.0 kB)
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BBR_205_1_315-318.pdf (193.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2011-05-19 | |||||
タイトル | ||||||
タイトル | The centrally acting non-narcotic antitussive tipepidine produces antidepressant-like effect in the forced swimming test in rats | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | Antidepressant-like effect, Antitussives, Dopamine, Forced swimming test, G-protein-coupled inwardly rectifying K+ (GIRK) channel, Tipepidine | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
川浦, 一晃
× 川浦, 一晃× Ogata, Yukino× Inoue, Masako× 本田, 宗吉× 副田, 二三夫× 白崎, 哲哉× 高濱, 和夫 |
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別言語の著者 |
川浦, 一晃
× 川浦, 一晃× 緒方, 雪乃× 井上, 雅子× 本田, 宗吉× 副田, 二三夫× 白崎, 哲哉× 高濱, 和夫 |
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内容記述 | ||||||
内容記述 | The antidepressant-like effect of tipepidine was studied in rats. Tipepidine at 20 and 40 mg/kg i.p. reduced immobility in the forced swimming test and tipepidine at 40mg/kg, i.p. increased climbing in the test. The drug at 40 mg/kg, i.p. had no effect on the loco-motor activity and motor coordination. These results suggest that tipepidine may be a novel drug with antidepressant-like activity. | |||||
書誌情報 |
Behavioural Brain Research 巻 205, 号 1, p. 315-318, 発行年 2009-12-14 |
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PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 19616036 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 10.1016/j.bbr.2009.07.004 | |||||
権利 | ||||||
権利情報 | © 2009 Elsevier B.V. | |||||
情報源(ISSN) | ||||||
関連名称 | 01664328 | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
形態 | ||||||
193131 bytes | ||||||
形態 | ||||||
27010 bytes | ||||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
日本十進分類法 | ||||||
主題 | 491.5 | |||||
出版者 | ||||||
出版者 | Elsevier B.V. | |||||
資源タイプ | ||||||
内容記述 | 論文(Article) | |||||
資源タイプ・ローカル | ||||||
雑誌掲載論文 | ||||||
資源タイプ・NII | ||||||
Journal Article | ||||||
資源タイプ・DCMI | ||||||
text | ||||||
資源タイプ・ローカル表示コード | ||||||
01 | ||||||
URL | ||||||
内容記述 | http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6SYP-4WSHJYV-2&_user=4545557&_coverDate=12%2F14%2F2009&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_acct=C000008298&_version=1&_urlVersion=0&_userid=4545557&md5=26594c82c885f2717dc79ebe9c6139f6&searchtype=a |