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Significant CMAP decrement by repetitive nerve stimulation is more frequent in median than ulnar nerves of patients with amyotrophic lateral sclerosis
http://hdl.handle.net/2298/26246
http://hdl.handle.net/2298/26246192eea2b-4d05-4669-b1ae-a735fb5285e5
名前 / ファイル | ライセンス | アクション |
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Muscle and Nerve.45.3.426-428.pdf (135.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-01-04 | |||||
タイトル | ||||||
タイトル | Significant CMAP decrement by repetitive nerve stimulation is more frequent in median than ulnar nerves of patients with amyotrophic lateral sclerosis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | amyotrophic lateral sclerosis, repetitive nerve stimulation, decremental motor responses, median nerve, ulnar nerve | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
Yamashita, Satoshi
× Yamashita, Satoshi× Sakaguchi, Hideya× Mori, Akira× 木村, 円× Maeda, Yasushi× Hirano, Teruyuki× Uchino, Makoto |
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別言語の著者 |
山下, 賢
× 山下, 賢× 坂口, 秀哉× 森, 麗× 木村, 円× 前田, 寧× 平野, 照之× 内野, 誠 |
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内容記述 | ||||||
内容記述 | Introduction: Several studies have shown a significant amplitude decrement in compound muscle action potentials (CMAP) on repetitive nerve stimulation (RNS) of muscles involved in ALS. In ALS, muscle wasting preferentially affects the thenar muscles (APB) rather than the hypothenar muscles (ADM). Methods: We performed RNS studies in the APB and ADM muscles of 32 ALS patients to determine whether the effect of RNS differs between the median and ulnar nerves. Results: The decremental responses to RNS were greater in the APB than in the ADM. Reduced CMAP amplitude was negatively correlated with CMAP decrement in median but not in ulnar nerves. Discussion: The greater CMAP decrement in median nerve was attributed to preferential involvement of the APB in the pathophysiology of ALS or some underlying difference in the biology of the two muscles/nerves. Further investigation may further our understanding of the pathophysiology of ALS. |
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書誌情報 |
Muscle and Nerve 巻 45, 号 3, p. 426-428, 発行年 2012-03 |
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ISSN | ||||||
収録物識別子 | 0148639X | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 22334178 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 10.1002/mus.22301 | |||||
権利 | ||||||
権利情報 | © 2012 John Wiley and Sons Inc | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
形態 | ||||||
135472 bytes | ||||||
形態 | ||||||
58382 bytes | ||||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
日本十進分類法 | ||||||
主題 | 493.6 | |||||
出版者 | ||||||
出版者 | John Wiley and Sons Inc. | |||||
資源タイプ | ||||||
内容記述 | 論文(Article) | |||||
資源タイプ・ローカル | ||||||
雑誌掲載論文 | ||||||
資源タイプ・NII | ||||||
Journal Article | ||||||
資源タイプ・DCMI | ||||||
text | ||||||
資源タイプ・ローカル表示コード | ||||||
01 | ||||||
URL | ||||||
内容記述 | http://onlinelibrary.wiley.com/doi/10.1002/mus.22301/abstract |