WEKO3
アイテム
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[{"creatorName": "木村, 和生", "creatorNameLang": "ja"}, {"creatorName": "キムラ, カズオ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Kimura, Kazuo", "creatorNameLang": "en"}], "familyNames": [{"familyName": "木村", "familyNameLang": "ja"}, {"familyName": "キムラ", "familyNameLang": "ja-Kana"}, {"familyName": "Kimura", "familyNameLang": "en"}], "givenNames": [{"givenName": "和生", "givenNameLang": "ja"}, {"givenName": "カズオ", "givenNameLang": "ja-Kana"}, {"givenName": "Kazuo", "givenNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "126584", "nameIdentifierScheme": "WEKO"}]}, {"creatorAffiliations": [{"affiliationNameIdentifiers": [{"affiliationNameIdentifier": "", "affiliationNameIdentifierScheme": "ISNI", "affiliationNameIdentifierURI": "http://www.isni.org/isni/"}], "affiliationNames": [{"affiliationName": "", "affiliationNameLang": "ja"}]}], "creatorNames": [{"creatorName": "梅村, 敏", "creatorNameLang": "ja"}, {"creatorName": "ウメムラ, サトシ", "creatorNameLang": "ja-Kana"}, {"creatorName": 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failure with normal left ventricular ejection fraction (LVEF). Obesity is one of\nthe major comorbid conditions of LVDD. Pericardial fat (PF) is an ectopic fat depot\nwith possible paracrine or mechanical effects on the coronary circulation and\n35 myocardial function.\nMethods We measured PF volume on 64 slice computed tomography and analyzed\nechocardiographic parameters to confirm LVDD in 229 consecutive patients suspected\nof coronary artery disease with LVEF of more than 50% and no symptomatic heart\nfailure (59% men, 67±12 years). LVDD was defined as the ratio of transmitral\n40 Doppler early filling velocity to tissue Doppler early diastolic mitral annular velocity\n(E/e’) \u003e10.\nResults PF volume correlated significantly with E/e’ (r=0.21, p\u003c0.01), left ventricular\nmass index (r=0.23, p\u003c0.001), and left atrial diameter (r=0.32, p\u003c0.001). The mean PF\nvolume was significantly greater in patients with LVDD (184±61 cm3, n=141) than in\n45 those without LVDD (154±58, n=88, p\u003c0.001). Multivariate logistic regression\nanalysis indicated that PF volume correlated significantly with the presence of LVDD\n(odds ratio: 2.00 per 100 cm3 increase in PF volume, p=0.02) independent of age,\ngender, abdominal obesity, hypertension, and diabetes.\nConclusions PF volumes are significantly associated with LVDD, independent of\n50 other factors such as hypertension or diabetes. PF may be implicated in the pathogenesis of LVDD in patients with normal LVEF.", "subitem_description_type": "Other"}]}, "item_16_description_77": {"attribute_name": "URL", "attribute_value_mlt": [{"subitem_description": "http://www.journal-of-cardiology.com/article/S0914-5087%2812%2900010-X/abstract@@@http://www.sciencedirect.com/science/article/pii/S091450871200010X", "subitem_description_type": "Other"}]}, "item_16_publisher_36": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Japanese College of Cardiology"}, {"subitem_publisher": "Elsevier"}]}, "item_16_relation_10": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "22365950", "subitem_relation_type_select": "PMID"}}]}, "item_16_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": 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Accumulation of Pericardial Fat Correlates with Left Ventricular Diastolic Dysfunction in Patients with Normal Ejection Fraction
http://hdl.handle.net/2298/29229
http://hdl.handle.net/2298/29229dcf3a364-39f6-4724-b2ba-5f2612e4bb5d
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Figures Marked Revision.pdf (197.0 kB)
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Table Marked Revision.pdf (63.1 kB)
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Manuscript.pdf (109.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-01-29 | |||||
タイトル | ||||||
タイトル | Accumulation of Pericardial Fat Correlates with Left Ventricular Diastolic Dysfunction in Patients with Normal Ejection Fraction | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | pericardium, obesity, diastole, heart failure | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
小西, 正紹
× 小西, 正紹× 杉山, 正悟× 菅村, 公一× 野崎, 俊光× 松原, 純一× 秋山, 英一× 宇都宮, 大輔× 松澤, 泰志× 山下, 康行× 木村, 和生× 梅村, 敏× 小川, 久雄 |
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別言語の著者 |
小西, 正紹
× 小西, 正紹× 杉山, 正悟× 菅村, 公一× 野崎, 俊光× 松原, 純一× 秋山, 英一× 宇都宮, 大輔× 松澤, 泰志× 山下, 康行× 木村, 和生× 梅村, 敏× 小川, 久雄 |
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内容記述 | ||||||
内容記述 | Background Left ventricular diastolic dysfunction (LVDD) plays an important role in heart failure with normal left ventricular ejection fraction (LVEF). Obesity is one of the major comorbid conditions of LVDD. Pericardial fat (PF) is an ectopic fat depot with possible paracrine or mechanical effects on the coronary circulation and 35 myocardial function. Methods We measured PF volume on 64 slice computed tomography and analyzed echocardiographic parameters to confirm LVDD in 229 consecutive patients suspected of coronary artery disease with LVEF of more than 50% and no symptomatic heart failure (59% men, 67±12 years). LVDD was defined as the ratio of transmitral 40 Doppler early filling velocity to tissue Doppler early diastolic mitral annular velocity (E/e’) >10. Results PF volume correlated significantly with E/e’ (r=0.21, p<0.01), left ventricular mass index (r=0.23, p<0.001), and left atrial diameter (r=0.32, p<0.001). The mean PF volume was significantly greater in patients with LVDD (184±61 cm3, n=141) than in 45 those without LVDD (154±58, n=88, p<0.001). Multivariate logistic regression analysis indicated that PF volume correlated significantly with the presence of LVDD (odds ratio: 2.00 per 100 cm3 increase in PF volume, p=0.02) independent of age, gender, abdominal obesity, hypertension, and diabetes. Conclusions PF volumes are significantly associated with LVDD, independent of 50 other factors such as hypertension or diabetes. PF may be implicated in the pathogenesis of LVDD in patients with normal LVEF. |
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書誌情報 |
Journal of Cardiology 巻 59, 号 3, p. 344-351, 発行年 2012-05 |
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ISSN | ||||||
収録物識別子 | 09145087 | |||||
書誌レコードID | ||||||
収録物識別子 | AN10070473 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 22365950 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 10.1016/j.jjcc.2012.01.006 | |||||
権利 | ||||||
権利情報 | Japanese College of Cardiology | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
フォーマット | ||||||
内容記述 | application/pdf | |||||
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著者版フラグ | ||||||
出版タイプ | AM | |||||
日本十進分類法 | ||||||
主題 | 493 | |||||
出版者 | ||||||
出版者 | Japanese College of Cardiology | |||||
出版者 | ||||||
出版者 | Elsevier | |||||
資源タイプ | ||||||
内容記述 | 論文(Article) | |||||
資源タイプ・ローカル | ||||||
雑誌掲載論文 | ||||||
資源タイプ・NII | ||||||
Journal Article | ||||||
資源タイプ・DCMI | ||||||
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資源タイプ・ローカル表示コード | ||||||
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URL | ||||||
内容記述 | http://www.journal-of-cardiology.com/article/S0914-5087%2812%2900010-X/abstract@@@http://www.sciencedirect.com/science/article/pii/S091450871200010X |