2026-03-14T02:06:34Z https://kumadai.repo.nii.ac.jp/oai

oai:kumadai.repo.nii.ac.jp:00025349 2026-02-25T01:48:39Z 343:344:345:346

Clarification of the mechanism of p53 inactivation by the novel HCV infection-related protein 3β-hydroxysterol Δ24-reductase 新規HCV関連因子 3β-hydroxysterol Δ24-reductase によるp53 機能抑制機構の解明 シンキ HCV カンレン インシ 3β hydroxysterol Δ24 reductase ニ ヨル p53 キノウ ヨクセイ キコウ ノ カイメイ 西村, 知裕 ニシムラ, トモヒロ Nishimura, Tomohiro 377.5 HCV DHCR24 The hepatitis C virus (HCV) is one of the most important causes of chronic liver disease. This chronic infection induces chronic hepatitis, hepatic cirrhosis and hematoma. The cause of the liver carcinoma is thought to be a long series of inflammation. But even now, the mechanism is not completely clarified. Thus I tried to analyzed host factor that was upregulated by the persistence expression of HCV genome, and elucidate of oncogenic mechanism of HCV infection. The purpose of this study was finding of new approach to the HCV therapy. 熊本大学 2011-02-22 eng thesis VoR http://hdl.handle.net/2298/21804 https://kumadai.repo.nii.ac.jp/records/25349 乙第939号 博士（医学） 2011-02-22 17401 熊本大学 https://kumadai.repo.nii.ac.jp/record/25349/files/32-0939.pdf application/pdf 2.5 MB 2020-03-02