{"created":"2023-06-19T09:06:14.551529+00:00","id":17043,"links":{},"metadata":{"_buckets":{"deposit":"185c116f-957a-4ae5-a88d-081d2831f3e5"},"_deposit":{"created_by":1,"id":"17043","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"17043"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00017043","sets":["343:344:345:346"]},"author_link":["78803","78802","78804"],"item_14_alternative_title_22":{"attribute_name":"その他の言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Effect of extracellular matrix protein on the rate of proteoglycan synthesis in rabbit intervertebral disc cells"}]},"item_14_alternative_title_23":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"サイボウガイキシツ　タンパク　ブンシ　ガ　カト　ツイカンバン　サイボウ　ノ　プロテオグリカン　ゴウセイノウ　ニ　アタエル　エイキョウ　ニ　カンスル　ジッケンテキ　ケンキュウ"}]},"item_14_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-02-17","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_14_creator_3":{"attribute_name":"別言語の著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Inoue, Tetsuji"}],"nameIdentifiers":[{"nameIdentifier":"78804","nameIdentifierScheme":"WEKO"}]}]},"item_14_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_14_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"学位論文(Thesis)","subitem_description_type":"Other"}]},"item_14_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"脊椎の変性に伴いさまざまな脊椎疾患を起こすようになるが、脊椎の変性は椎間板から始まるといわれている。加齢とともに特に髄核内のproteoglycanの含有量が減少することが椎間板の変性に大きく影響しているのは事実である。従って、椎間板細胞のプロテオグリカンの合成のメカニズムが明らかになれば、変性の予防、治療につながることが期待される。そこで椎間板に豊富に存在し基本的細胞活動に非常に重要である細胞外基質蛋白が椎間板細胞の細胞増殖及び代謝にいかなる影響があるのか明らかにすることを目的とした。","subitem_description_type":"Other"}]},"item_14_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本大学"}]},"item_14_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"377.5","subitem_subject_scheme":"NDC"}]},"item_14_text_18":{"attribute_name":"形態","attribute_value_mlt":[{"subitem_text_value":"1404277 bytes"}]},"item_14_text_47":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"博士論文"}]},"item_14_text_48":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Thesis or Dissertation"}]},"item_14_text_49":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_14_text_50":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"03"}]},"item_14_text_81":{"attribute_name":"学位番号","attribute_value_mlt":[{"subitem_text_value":"乙博医第873号"}]},"item_14_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"井上, 哲二"}],"nameIdentifiers":[{"nameIdentifier":"78802","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-28"}],"displaytype":"detail","filename":"32-0873.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"32-0873.pdf","url":"https://kumadai.repo.nii.ac.jp/record/17043/files/32-0873.pdf"},"version_id":"5030cfb1-cd09-48a3-8f4b-545901fb63a9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"細胞外基質蛋白分子が家兎椎間板細胞のプロテオグリカン合成能に与える影響に関する実験的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"細胞外基質蛋白分子が家兎椎間板細胞のプロテオグリカン合成能に与える影響に関する実験的研究"}]},"item_type_id":"14","owner":"1","path":["346"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-11-06"},"publish_date":"2014-11-06","publish_status":"0","recid":"17043","relation_version_is_last":true,"title":["細胞外基質蛋白分子が家兎椎間板細胞のプロテオグリカン合成能に与える影響に関する実験的研究"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T19:20:40.900023+00:00"}