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Marine natural products that inhibit osteoclastogenesis and promote osteoblast differentiation
http://hdl.handle.net/2298/0002000047
http://hdl.handle.net/2298/0002000047751d813f-fc58-41a9-aff8-c0426186a43e
| 名前 / ファイル | ライセンス | アクション |
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s11418-022-01622-5.pdf (753 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2023-11-14 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Marine natural products that inhibit osteoclastogenesis and promote osteoblast differentiation | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | Marine organisms, Osteoporosis, Osteoclast, Osteoblast, RANKL, TRAP | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 著者 |
Ahmed, H. H. El-Desoky
× Ahmed, H. H. El-Desoky
× 塚本, 佐知子
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| 内容記述 | ||||||||||||||
| 内容記述 | Osteoporosis is a disease that affects the quality of life of elderly people. The balance between bone formation mediated by osteoblasts and bone resorption by osteoclasts is important to maintain the normal bone condition. Therefore, the promotion of osteoblast differentiation and the suppression of osteoclastogenesis are effective strategies for osteoporosis treatment. Marine organisms are a promising source of biologically active and structurally diverse secondary metabolites, and have been providing drug leads for the treatment of numerous diseases. We describe the marine-derived secondary metabolites that can inhibit receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and promote osteoblast differentiation. | |||||||||||||
| 書誌情報 |
en : Journal of Natural Medicines 巻 76, p. 575-583, 発行年 2022-04-10 |
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| ISSN | ||||||||||||||
| 収録物識別子 | 1340-3443 | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||
| 関連識別子 | https://doi.org/10.1007/s11418-022-01622-5 | |||||||||||||
| 権利 | ||||||||||||||
| 権利情報 | (C) 2022, The Author(s) | |||||||||||||
| 著者版フラグ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | Springer Nature | |||||||||||||
| 言語 | en | |||||||||||||
