| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2023-11-15 |
| タイトル |
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タイトル |
Halichonic Acid B, a Rearranged Nitrogenous Bisabolene-Type Sesquiterpene from a Marine Sponge Axinyssa sp. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
marine sponge, Axinyssa species, nitrogenous bisabolone-type sesquiterpene |
| 資源タイプ |
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資源タイプ |
journal article |
| 著者 |
Yuki, Hitora
Kenta, Ogura
Ahmed, H. H. El-Desoky
Yuji, Ise
Esther, D. Angkouw
Remy, E. P. Mangindaan
塚本, 佐知子
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| 内容記述 |
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内容記述 |
A new rearranged nitrogenous bisabolone-type sesquiterpene, halichonic acid B (1), was isolated from a marine sponge Axinyssa sp. together with halichonic acid (2) and (6R,7S)-7-amino-7,8-dihydro-α-bisabolene (3). The structure of 1 was determined by extensive NMR and MS analyses, revealing an unprecedented carbon framework, and its absolute configuration was elucidated by time-dependent density-functional theory (TDDFT)-based electronic circular dichroism (ECD) spectrum calculation. We propose that 1 and 2 may be biosynthesized in the same pathway, involving the reaction between farnesyl pyrophosphate and glycine, followed by cyclization. |
| 書誌情報 |
en : Chemical and Pharmaceutical Bulletin
巻 69,
号 8,
p. 802-805,
発行年 2021-08-01
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| ISSN |
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収録物識別子 |
0009-2363 |
| DOI |
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関連タイプ |
isIdenticalTo |
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関連識別子 |
https://doi.org/10.1248/cpb.c21-00392 |
| 権利 |
|
|
権利情報 |
(C)2021 The Pharmaceutical Society of Japan |
| 著者版フラグ |
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出版タイプ |
VoR |
| 出版者 |
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出版者 |
The Pharmaceutical Society of Japan |
|
言語 |
en |
69_c21-00392.pdf (550 KB)
