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アイテム
Kidney Bioengineering for Transplantation
http://hdl.handle.net/2298/0002000772
http://hdl.handle.net/2298/0002000772c13a6076-1742-49cb-b652-142c7fc378ae
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10.1097_TP.0000000000004526.pdf (430.2 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2025-01-09 | |||||||||
| タイトル | ||||||||||
| タイトル | Kidney Bioengineering for Transplantation | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 著者 |
Yutaro, Ibi
× Yutaro, Ibi
× Ryuichi, Nishinakamura
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| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | The kidney is an important organ for maintenance of homeostasis in the human body. As renal failure progresses, renal replacement therapy becomes necessary. However, there is a chronic shortage of kidney donors, creating a major problem for transplantation. To solve this problem, many strategies for the generation of transplantable kidneys are under investigation. Since the first reports describing that nephron progenitors could be induced from human induced pluripotent stem cells, kidney organoids have been attracting attention as tools for studying human kidney development and diseases. Because the kidney is formed through the interactions of multiple renal progenitors, current studies are investigating ways to combine these progenitors derived from human induced pluripotent stem cells for the generation of transplantable kidney organoids. Other bioengineering strategies, such as decellularization and recellularization of scaffolds, 3-dimensional bioprinting, interspecies blastocyst complementation and progenitor replacement, and xenotransplantation, also have the potential to generate whole kidneys, although each of these strategies has its own challenges. Combinations of these approaches will lead to the generation of bioengineered kidneys that are transplantable into humans. | |||||||||
| bibliographic_information |
en : Transplantation 巻 107, 号 9, p. 1883-1894, 発行年 2023-09 |
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| 収録物識別子 | 0041-1337 | |||||||||
| item_16_relation_11 | ||||||||||
| 関連タイプ | isVersionOf | |||||||||
| 関連識別子 | https://doi.org/10.1097/TP.0000000000004526 | |||||||||
| 権利 | ||||||||||
| 権利情報 | (C) 2023 Wolters Kluwer Health, Inc. All rights reserved. | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
| 出版者 | ||||||||||
| 出版者 | Wolters Kluwer Health, Inc. | |||||||||
