{"created":"2023-06-19T09:10:45.171234+00:00","id":22293,"links":{},"metadata":{"_buckets":{"deposit":"48f2874c-12f0-43f3-8516-1b214329a740"},"_deposit":{"created_by":127,"id":"22293","owners":[127],"pid":{"revision_id":0,"type":"depid","value":"22293"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00022293","sets":["343:344:345:346"]},"author_link":[],"item_14_biblio_info_6":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-11","bibliographicIssueDateType":"Issued"}}]},"item_14_date_granted_74":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2008-03-11"}]},"item_14_degree_grantor_72":{"attribute_name":"item_14_degree_grantor_72","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"熊本大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17401","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_14_degree_name_71":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_14_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Combination anti-retroviral drug regimens including reverse-transcriptase inhibitors and protease inhibitors have dramatically decreased morbidity and mortality rates in human immunodeficiency type 1 virus (HIV-1) infected individuals. However, it is reported that these combination therapies induce many side effects and have aided the emergence of strains of resistant HIV-1. In this study, we examined the inhibitory effect of electrical stimulation on infection of HIV-1 and the growth of chronically HIV-1-infected cells. I then investigated new inhibition factors of HIV-1.","subitem_description_language":"en","subitem_description_type":"Other"},{"subitem_description":"本研究では、従来の方法とは全く異なる細胞への電位印加というアプローチで、HIV-1持続感染細胞の増殖とHIV-1の感染性に関する抑制効果を調べ、新たなウイルス抑制要因を探った。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_14_dissertation_number_75":{"attribute_name":"dissertation_number","attribute_value_mlt":[{"subitem_dissertationnumber":"乙医学第910号"}]},"item_14_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本大学","subitem_publisher_language":"ja"}]},"item_14_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"377.5","subitem_subject_scheme":"NDC"}]},"item_14_text_81":{"attribute_name":"学位番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"乙博医学第910号"}]},"item_14_version_type_19":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"熊谷, エツ子","creatorNameLang":"ja"},{"creatorName":"クマガイ, エツコ","creatorNameLang":"ja-Kana"},{"creatorName":"Kumagai, Etsuko","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-03-02"}],"displaytype":"detail","filename":"32-0910.pdf","filesize":[{"value":"4.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"32-0910.pdf","url":"https://kumadai.repo.nii.ac.jp/record/22293/files/32-0910.pdf"},"version_id":"2ffea527-5f30-4274-b868-7aae561ed8d3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HIV-1持続感染細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"低電位印加","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"HIV-1初感染細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"HIV-1吸着細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"活性酸素種","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞膜","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ウイルスエンベロープ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"電位印加によるヒト免疫不全ウイルスの感染と持続感染細胞の増殖に関する抑制効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"電位印加によるヒト免疫不全ウイルスの感染と持続感染細胞の増殖に関する抑制効果","subitem_title_language":"ja"},{"subitem_title":"デンイ インカ ニ ヨル ヒト メンエキ フゼン ウイルス ノ カンセン ト ジゾク カンセン サイボウ ノ ゾウショク ニ カンスル ヨクセイ コウカ","subitem_title_language":"ja-Kana"},{"subitem_title":"Inhibitory effect of electrical stimulation on infection of human immunodeficiency virus type 1 (HIV-1) and growth of chronically HIV-1-infected cells","subitem_title_language":"en"}]},"item_type_id":"14","owner":"127","path":["346"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-08-12"},"publish_date":"2014-08-12","publish_status":"0","recid":"22293","relation_version_is_last":true,"title":["電位印加によるヒト免疫不全ウイルスの感染と持続感染細胞の増殖に関する抑制効果"],"weko_creator_id":"127","weko_shared_id":-1},"updated":"2025-05-19T04:39:15.904806+00:00"}