{"created":"2023-06-19T09:11:00.817420+00:00","id":22620,"links":{},"metadata":{"_buckets":{"deposit":"ed1d32b8-e2db-4f43-842a-e044e3ff023e"},"_deposit":{"created_by":1,"id":"22620","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"22620"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00022620","sets":["343:344:345:485"]},"author_link":["98247","98248","98246"],"item_14_alternative_title_22":{"attribute_name":"その他の言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Probing the hydrolysis mechanism of metallo-β-lactamases and development of their irreversible inhibitors"}]},"item_14_alternative_title_23":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"シンコウ ヤクザイ タイセイキン ガ サンセイ スル メタロ-β-ラクタマーゼ ノ カスイ ブンカイ キコウ ノ カイメイ ト ヒカギャクテキ ソガイザイ ノ カイハツ"}]},"item_14_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-10-06","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{}]}]},"item_14_creator_3":{"attribute_name":"別言語の著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamaguchi, Yoshihiro"}],"nameIdentifiers":[{"nameIdentifier":"98248","nameIdentifierScheme":"WEKO"}]}]},"item_14_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_14_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"学位論文(Thesis)","subitem_description_type":"Other"}]},"item_14_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"The aims of this study were to clarify the common hydrolysis mechanism of MBLs using kinetics and X-ray crystallographic studies and to develop mechanism-based irreversible inhibitors for all MBLs and agents for detecting MBL-producing strains with high sensitivity and selectivity.","subitem_description_type":"Other"}]},"item_14_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本大学"}]},"item_14_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"377.5","subitem_subject_scheme":"NDC"}]},"item_14_text_18":{"attribute_name":"形態","attribute_value_mlt":[{"subitem_text_value":"3935311 bytes"}]},"item_14_text_47":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"博士論文"}]},"item_14_text_48":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Thesis or Dissertation"}]},"item_14_text_49":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_14_text_50":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"03"}]},"item_14_text_78":{"attribute_name":"コメント","attribute_value_mlt":[{"subitem_text_value":"熊本大学大学院医学薬学研究科"}]},"item_14_text_81":{"attribute_name":"学位番号","attribute_value_mlt":[{"subitem_text_value":"乙博薬第109号"}]},"item_14_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山口, 佳宏"}],"nameIdentifiers":[{"nameIdentifier":"98246","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-02"}],"displaytype":"detail","filename":"33-109.pdf","filesize":[{"value":"3.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"33-109.pdf","url":"https://kumadai.repo.nii.ac.jp/record/22620/files/33-109.pdf"},"version_id":"1cc79587-f19b-4103-88d2-ff4aab6b4e49"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"metallo-β-lactamase","subitem_subject_scheme":"Other"},{"subitem_subject":"IMP-1","subitem_subject_scheme":"Other"},{"subitem_subject":"Zn(II)イオン","subitem_subject_scheme":"Other"},{"subitem_subject":"加水分解活性","subitem_subject_scheme":"Other"},{"subitem_subject":"Asp120(81)","subitem_subject_scheme":"Other"},{"subitem_subject":"X線結晶構造解析","subitem_subject_scheme":"Other"},{"subitem_subject":"蛍光スペクトル","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"新興薬剤耐性菌が産生するメタロ-β-ラクタマーゼの加水分解機構の解明と非可逆的阻害剤の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新興薬剤耐性菌が産生するメタロ-β-ラクタマーゼの加水分解機構の解明と非可逆的阻害剤の開発"}]},"item_type_id":"14","owner":"1","path":["485"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-08-24"},"publish_date":"2009-08-24","publish_status":"0","recid":"22620","relation_version_is_last":true,"title":["新興薬剤耐性菌が産生するメタロ-β-ラクタマーゼの加水分解機構の解明と非可逆的阻害剤の開発"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T18:50:13.501970+00:00"}