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Event-related potentials in Japanese childhood chronic fatigue syndrome
http://hdl.handle.net/2298/15257
http://hdl.handle.net/2298/1525778b5ca09-61cc-4b8f-8421-a59c40059261
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
JPN5-2007r.pdf (3.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2010-07-07 | |||||
| タイトル | ||||||
| タイトル | Event-related potentials in Japanese childhood chronic fatigue syndrome | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題 | Childhood type chronic fatigue syndrome, Frontal lobe function, Electrocardiographic R-R interval, Event-related potential, P300 | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
友田, 明美
× 友田, 明美 |
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| 別言語の著者 |
友田, 明美
× 友田, 明美 |
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| 内容記述 | ||||||
| 内容記述 | The aim of this study was to investigate cognitive functions such as allocation and information processing in patients with childhood type chronic fatigue syndrome (CCFS) using event-related potentials. A total of 190 healthy children as controls and 414 patients with CCFS participated in this study. Both patients and controls had (i) event-related potentials (including P300, P100, N150 and P200 measurements); (ii) component analysis of electrocardiographic R-R interval to evaluate autonomic function; and (iii) KANA-Pick-out test to evaluate frontal lobe function. The cutoff threshold defining abnormal P300 latency to target stimuli and amplitude to non-target stimuli was set at two standard deviations above the mean values of controls. Forty patients (classified as Type-I) had an abnormally-prolonged P300 latency to target stimuli, and 49 patients (classified as Type-II) had an abnormally-exaggerated P300 amplitude, and the remaining 325 patients whose P300 latency and amplitude ranged below the above-mentioned threshold were classified as Type-III. All patient groups had normal P100, N150 and P200 measurements. Component analysis of electrocardiographic R-R intervals revealed that the power of high-frequency components was lower in all patient groups, compared to controls. The score in KANA-Pick-out test was worse in all patient groups compared to controls; Type-I Group had the worst score and Type-II Group had the best score among the patients. Taken together, we speculate that abnormally-prolonged P300 latency to target stimuli might be associated with learning disability and abnormallyexaggerated P300 amplitude to non-target stimuli might be associated with hypersensitivity such as phobia in patients with CCFS. Psychosomatic symptoms in patients with CCFS might be associated with higher-order level cognitive dysfunction. |
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| 書誌情報 |
Journal of Pediatric Neurology 巻 5, p. 199-208, 発行年 2007 |
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| 権利 | ||||||
| 権利情報 | © 2007 - IOS Press and the authors. All rights reserved | |||||
| 情報源(ISSN) | ||||||
| 関連名称 | 1304-2580 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 3632045 bytes | ||||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 493.9 | |||||
| 出版者 | ||||||
| 出版者 | IOS Press | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 雑誌掲載論文 | ||||||
| 資源タイプ・NII | ||||||
| Journal Article | ||||||
| 資源タイプ・DCMI | ||||||
| text | ||||||
| 資源タイプ・ローカル表示コード | ||||||
| 01 | ||||||
