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Exposure to parental verbal abuse is associated with increased gray matter volume in superior temporal gyrus
http://hdl.handle.net/2298/17488
http://hdl.handle.net/2298/17488e655ac56-4203-4d8b-9c6b-27534b3fd26a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Tomoda_VA_Neuroimage_2010r.pdf (9.5 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2011-01-05 | |||||
| タイトル | ||||||
| タイトル | Exposure to parental verbal abuse is associated with increased gray matter volume in superior temporal gyrus | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
友田, 明美
× 友田, 明美× Sheu, Yi-Shin× Rabi, Keren× 鈴木, 華子× Navalta, Carryl P.× Polcari, Ann× Teicher, Martin H. |
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| 別言語の著者 |
友田, 明美
× 友田, 明美 |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Objective: Exposure to parental verbal aggression (PVA) during childhood increases risk for the development of psychopathology, particularly mood and anxiety disorders. Other forms of childhood abuse have been found to be associated with alterations in brain structure. The aim of this study was to ascertain whether exposure to PVA was associated with discernible effects on brain morphology. Methods: Optimized voxel-based morphometry was performed on 21 unmedicated, right-handed subjects (18-25 years) with histories of PVA and 19 psychiatrically healthy controls of comparable age and gender. Group differences in gray matter volume (GMV) - covaried by age, gender, parental education, financial stress, and total GMV - were assessed using high-resolution, T1-weighted, volumetric MRI data sets (Siemens 3T trio scanner). Results: GMV was increased by 14.1% in the left superior temporal gyrus (STG, BA 22) (P = 0.004, corrected cluster level). GMV in this cluster was associated most strongly with levels of maternal ( ß = 0.544, P < 0.0001) and paternal ( ß = 0.300, P < 0.02) verbal aggression and inversely associated with parental education ( ß = - 0.577, P < 0.0001). Conclusion: Previous studies have demonstrated an increase in STG GMV in children with abuse histories, and found a reduction in fractional anisotropy in the arcuate fasciculus connecting Wernicke's and frontal areas in young adults exposed to PVA. These findings and the present results suggest that the development of auditory association cortex involved in language processing may be affected by exposure to early stress and/or emotionally abusive language. | |||||
| 書誌情報 |
NeuroImage 巻 54, 号 Supplement 1, p. S280-S286, 発行年 2011-01 |
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| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | 10.1016/j.neuroimage.2010.05.027 | |||||
| 権利 | ||||||
| 権利情報 | © 2010 Elsevier Inc. | |||||
| 情報源(ISSN) | ||||||
| 関連名称 | 10538119 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 値 | 9451795 bytes | |||||
| 形態 | ||||||
| 値 | 58407 bytes | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 493.9 | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 値 | 雑誌掲載論文 | |||||
| 資源タイプ・NII | ||||||
| 値 | Journal Article | |||||
| 資源タイプ・DCMI | ||||||
| 値 | text | |||||
| 資源タイプ・ローカル表示コード | ||||||
| 値 | 01 | |||||
| URL | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WNP-503GHCF-6&_user=4545557&_coverDate=05%2F17%2F2010&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000008298&_version=1&_urlVersion=0&_userid=4545557&md5=ee3a0fe2f1e54ff3ee9d283656a86ef0 | |||||
