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Reduced prefrontal cortical gray matter volume in young adults exposed to harsh corporal punishment
http://hdl.handle.net/2298/15289
http://hdl.handle.net/2298/1528992b74e68-dbb5-4525-ac4c-ebb7eef2cee0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Neuroimage_MS_CP_2009r.pdf (226.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2010-07-08 | |||||
| タイトル | ||||||
| タイトル | Reduced prefrontal cortical gray matter volume in young adults exposed to harsh corporal punishment | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Corporal punishment (CP), Harsh corporal punishment (HCP), Voxel-based morphometry (VBM), Gray matter volume (GMV), Medial prefrontal cortex (MPFC), Dorsolateral prefrontal cortex (DLPFC), Anterior cingulate gyrus (AC), MRPFC (medial rostral prefrontal cortex) | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 別言語の著者 |
友田, 明美
× 友田, 明美× 鈴木, 華子× Rabi, Keren× Sheu, Yi-Shin× Polcari, Ann× Teicher, Martin H. |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Objective:Harsh corporal punishment (HCP) during childhood is a chronic, developmental stressor associated with depression, aggression and addictive behaviors. Exposure to traumatic stressors, such as sexual abuse, is associated with alteration in brain structure, but nothing is known about the potential neurobiological consequences of HCP. The aim of this study was to investigate whether HCP was associated with discernible alterations in gray matter volume (GMV) using voxel-based morphometry (VBM). Methods: 1455 young adults (18?25 years) were screened to identify 23 with exposure to HCP (minimum 3 years duration, 12 episodes per year, frequently involving objects) and 22 healthy controls. High-resolution T1-weighted MRI datasets were obtained using Siemens 3 T trio scanner. Results: GMV was reduced by 19.1% in the right medial frontal gyrus (medial prefrontal cortex; MPFC, BA10) (P=0.037, corrected cluster level), by 14.5% in the left medial frontal gyrus (dorsolateral prefrontal cortex; DLPFC, BA9) (P=0.015, uncorrected cluster level) and by 16.9% in the right anterior cingulate gyrus (BA24) (Pb0.001, uncorrected cluster level) of HCP subjects. There were significant correlations between GMV in these identified regions and performance IQ on the WAIS-III. Conclusions: Exposing children to harsh HCP may have detrimental effects on trajectories of brain development. However, it is also conceivable that differences in prefrontal cortical development may increase risk of exposure to HCP. |
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| 書誌情報 |
NeuroImage 巻 47, 号 SUPPL. 2, p. T66-T71, 発行年 2009-08 |
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| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | https://doi.org/10.1016/j.neuroimage.2009.03.005 | |||||
| 権利 | ||||||
| 権利情報 | © 2009 Elsevier Inc. | |||||
| 情報源(ISSN) | ||||||
| 関連名称 | 10538119 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 値 | 226282 bytes | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 493.9 | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 値 | 雑誌掲載論文 | |||||
| 資源タイプ・NII | ||||||
| 値 | Journal Article | |||||
| 資源タイプ・DCMI | ||||||
| 値 | text | |||||
| 資源タイプ・ローカル表示コード | ||||||
| 値 | 01 | |||||
