{"created":"2023-06-19T09:12:20.913340+00:00","id":24170,"links":{},"metadata":{"_buckets":{"deposit":"20d9259e-0bef-4ae0-a2b7-1744cc0650c5"},"_deposit":{"created_by":1,"id":"24170","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"24170"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00024170","sets":["413:414","585:610:1247"]},"author_link":["158961","158233","158962","158960","158965"],"item_15_alternative_title_22":{"attribute_name":"その他の言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Relationship between Clinical Types and Intracellular pH of Leukemic Cells in Adult T-Cell Leukemia"}]},"item_15_alternative_title_23":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"セイジン Ｔ サイボウ ハッケツビョウ ノ リンショウ ビョウ カタ ト ハッケツビョウ サイボウ ナイ ｐＨ ト ノ カンケイ"}]},"item_15_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-03-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"65","bibliographicPageStart":"59","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"熊本大学医療技術短期大学部紀要"}]}]},"item_15_creator_3":{"attribute_name":"別言語の著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"石井, 俊徳","creatorNameLang":"ja"},{"creatorName":"イシイ, トシノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Ishii, Toshinori","creatorNameLang":"en"}],"familyNames":[{"familyName":"石井","familyNameLang":"ja"},{"familyName":"イシイ","familyNameLang":"ja-Kana"},{"familyName":"Ishii","familyNameLang":"en"}],"givenNames":[{"givenName":"俊徳","givenNameLang":"ja"},{"givenName":"トシノリ","givenNameLang":"ja-Kana"},{"givenName":"Toshinori","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"158233","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"我孫子, わかな","creatorNameLang":"ja"},{"creatorName":"アビコ, ワカナ","creatorNameLang":"ja-Kana"},{"creatorName":"Abiko, Wakana","creatorNameLang":"en"}],"familyNames":[{"familyName":"我孫子","familyNameLang":"ja"},{"familyName":"アビコ","familyNameLang":"ja-Kana"},{"familyName":"Abiko","familyNameLang":"en"}],"givenNames":[{"givenName":"わかな","givenNameLang":"ja"},{"givenName":"ワカナ","givenNameLang":"ja-Kana"},{"givenName":"Wakana","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"158961","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamaguchi, Kaori"}],"nameIdentifiers":[{"nameIdentifier":"158965","nameIdentifierScheme":"WEKO"}]}]},"item_15_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_15_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"論文(Article)","subitem_description_type":"Other"}]},"item_15_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"成人T細胞白血病はhuman T cell lymphotrophic virus I 感染と密接に関連していると考えられている成熟Ｔ細胞の白血病で、通常はウィルス感染後数年から数十年の経過でキャリアー、くすぶり型、慢性型を経て急性型へと進展重症化する。キャリアーでは腫瘍細胞は認められないが、くすぶり型では少数の白血病細胞が末梢血に出現し、慢性型と急性型ではリンパ球の大多数が腫瘍細胞である。臨床的には急性型は慢性型と異なり、急激な細胞の増殖や臓器浸潤、高カルシウム血症がみられることから、同じ腫瘍細胞でありながら急性型と慢性型ではALT細胞に質的な変化が生じているのではないかと推測される。そこで細胞増殖に関わりを持つpHiにこの質的な変化が反映されていないかどうかを明らかにするために、pHiとALTの臨床病型との関係について検討した。","subitem_description_type":"Other"}]},"item_15_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本大学"}]},"item_15_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09181512","subitem_source_identifier_type":"ISSN"}]},"item_15_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10401515","subitem_source_identifier_type":"NCID"}]},"item_15_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"493.173","subitem_subject_scheme":"NDC"}]},"item_15_text_18":{"attribute_name":"形態","attribute_value_mlt":[{"subitem_text_value":"1958406 bytes"}]},"item_15_text_47":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"紀要論文"}]},"item_15_text_48":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Departmental Bulletin Paper"}]},"item_15_text_49":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_15_text_50":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"02"}]},"item_15_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"石井, 俊徳"}],"nameIdentifiers":[{"nameIdentifier":"158960","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"我孫子, わかな","creatorNameLang":"ja"},{"creatorName":"アビコ, ワカナ","creatorNameLang":"ja-Kana"},{"creatorName":"Abiko, Wakana","creatorNameLang":"en"}],"familyNames":[{"familyName":"我孫子","familyNameLang":"ja"},{"familyName":"アビコ","familyNameLang":"ja-Kana"},{"familyName":"Abiko","familyNameLang":"en"}],"givenNames":[{"givenName":"わかな","givenNameLang":"ja"},{"givenName":"ワカナ","givenNameLang":"ja-Kana"},{"givenName":"Wakana","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"158961","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山口, 佳織"}],"nameIdentifiers":[{"nameIdentifier":"158962","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-02"}],"displaytype":"detail","filename":"MT0006_059-065.pdf","filesize":[{"value":"2.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"MT0006_059-065.pdf","url":"https://kumadai.repo.nii.ac.jp/record/24170/files/MT0006_059-065.pdf"},"version_id":"00f42762-3f68-4e42-996e-ff9ce6efa14d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Adult T-cell Leukemia (ALT)","subitem_subject_scheme":"Other"},{"subitem_subject":"Clinical Type","subitem_subject_scheme":"Other"},{"subitem_subject":"Intracellular pH (pHi)","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"成人Ｔ細胞白血病の臨床病型と白血病細胞内ｐＨとの関係","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"成人Ｔ細胞白血病の臨床病型と白血病細胞内ｐＨとの関係"}]},"item_type_id":"15","owner":"1","path":["414","1247"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-11-09"},"publish_date":"2010-11-09","publish_status":"0","recid":"24170","relation_version_is_last":true,"title":["成人Ｔ細胞白血病の臨床病型と白血病細胞内ｐＨとの関係"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-09-05T06:29:20.157990+00:00"}