@article{oai:kumadai.repo.nii.ac.jp:00024178,
 author = {石井, 俊徳 and Ishii, Toshinori and 石井, 俊徳 and Ishii, Toshinori},
 journal = {熊本大学医学部保健学科紀要},
 month = {Jan},
 note = {application/pdf, 論文(Article), SLEにおいてリンパ球減少は診断および活動性評価の重要な所見である。リンパ球ROSとリンパ球減少との関係を調べてみた結果、有意の負の相関がみられた。またROSはFas陽性率やアポトーシス発現率と正の相関がみられた。この結果はROSがリンパ球減少を引き起こすアポトーシス経路に密接に関わっていることを示唆している。, Lymphocytopenia is an important laboratory finding in diagnosis and disease activity estimation of systemic lupus erythematosus. Here, I demonstrated that the amount of reactive oxygen species (ROS) produced by lymphocytes was negatively correlated with the number of lymphocytes in peripheral blood, and that the former was also positively correlated with both Fas positive rates and apoptosis rates of lymphocytes. These results suggest that ROS is necessary for the process of apoptosis which triggers lymphocytopenia in systemic lupus erythematosus.},
 pages = {47--53},
 title = {全身性エリテマトーデスにおけるリンパ球減少とリンパ球活性酸素の関係},
 volume = {2},
 year = {2006},
 yomi = {イシイ, トシノリ and イシイ, トシノリ}
}