@article{oai:kumadai.repo.nii.ac.jp:00024187,
 author = {関, 大亮 and 小幡, 晋平 and 白水, 剛 and 北野, 健 and 斉藤, 寿仁 and Saito, Hisato and Seki, Daisuke and Obata, Shinpei and Shirozu, Tsuyoshi and 北野, 健 and Kitano, Takeshi and 斉藤, 寿仁 and Saito, Hisato},
 issue = {9-10},
 journal = {Biochemical Genetics},
 month = {Oct},
 note = {application/pdf, 論文(Article), At least four paralogs of the small ubiquitin-related modifier (SUMO) exist in humans, but there is limited information about SUMO paralogs from other vertebrate species. We isolated the four cDNA encoding proteins, similar to human SUMOs, from the medaka fish, Oryzias latipes:  OlSUMO-1, OlSUMO-2, OlSUMO-3, and OlSUMO-4. The amino acid sequences of OlSUMO-2, OlSUMO-3 and OlSUMO-4 are 89‒94% identical, but they share only 45% identity with OlSUMO-1. Phylogenetic analysis, transient expression of OlSUMOs in cultured cells and in vitro binding of OlSUMOs with two different SUMO-interacting proteins demonstrated that the medaka SUMO paralogs can be grouped into two subfamilies, OlSUMO-1 and OlSUMO-2/3/4, respectively. Furthermore, this is the first report of all four OlSUMO transcripts being expressed in medaka embryos, implying that they have a role in fish development. The study will improve understanding of the relationship between structural and functional diversity of SUMO paralogs during vertebrate evolution., http://www.springerlink.com/content/p7h80l28340t5271/},
 pages = {737--750},
 title = {Identification of four sumo paralogs in the medaka fish, oryzias latipes, and their classification into two subfamilies},
 volume = {48},
 year = {2010},
 yomi = {サイトウ, ヒサト and キタノ, タケシ and サイトウ, ヒサト}
}