{"created":"2023-06-19T09:12:40.087390+00:00","id":24534,"links":{},"metadata":{"_buckets":{"deposit":"3e950e1c-0b6e-44bb-9ce5-37771dc3d2d7"},"_deposit":{"created_by":1,"id":"24534","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"24534"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00024534","sets":["413:443"]},"author_link":["109347","109348","109346","109349","109343","109350","109351","109345","109344"],"item_16_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"33","bibliographicPageStart":"27","bibliographicVolumeNumber":"56","bibliographic_titles":[{"bibliographic_title":"Journal of Nutritional Science and Vitaminology"}]}]},"item_16_creator_3":{"attribute_name":"別言語の著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"舩越, 弥生"}],"nameIdentifiers":[{"nameIdentifier":"109349","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大森, 久光"}],"nameIdentifiers":[{"nameIdentifier":"109350","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"加藤, 貴彦"}],"nameIdentifiers":[{"nameIdentifier":"109351","nameIdentifierScheme":"WEKO"}]}]},"item_16_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_16_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"論文(Article)","subitem_description_type":"Other"}]},"item_16_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Bone mineral density (BMD) reflects both genetic and lifestyle factors. The aim of this cross-sectional study was to investigate the influence of vitamin D receptor (VDR) gene polymorphism and lifestyle factors on BMD in premenopausal female workers. The subjects were 162 premenopausal female employees aged 22-44 y who worked at a large-scale integrated manufacturing facility in Japan. BMD was measured at the nondominant radius by dual energy X-ray absorptiometry. Lifestyle information was obtained by a questionnaire at the same time and genomic DNA was isolated from peripheral leukocytes. BMD was positively correlated with age, weight, and body mass index (BMI). The genotype frequencies of VDR gene polymorphism detected by TaqI analysis were 77.2, 22.8, and 0.0% for TT, Tt, and tt, respectively. Analysis of covariance with adjustment for age and BMI showed that the mean BMD was significantly lower in subjects with the Tt genotype than in those with the TT genotype. Subjects who drank alcohol also showed a significantly lower BMD if they had the Tt genotype than if they had the TT genotype. According to multiple linear regression analysis, the independent determinants of BMD were age, BMI, and VDR gene polymorphism. Our data show that BMD is negatively correlated with the Tt genotype of the VDR gene, but positively correlated with age and BMI. These findings suggest that analysis of VDR gene polymorphism may be useful for identifying individuals who are susceptible to osteoporosis so that early preventive measures can be provided.","subitem_description_type":"Other"}]},"item_16_description_77":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_description":"http://www.jstage.jst.go.jp/article/jnsv/56/1/56_27/_article/-char/ja/","subitem_description_type":"Other"}]},"item_16_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"社団法人日本栄養・食糧学会"},{"subitem_publisher":"日本ビタミン学会"}]},"item_16_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3177/jnsv.56.27","subitem_relation_type_select":"DOI"}}]},"item_16_relation_16":{"attribute_name":"情報源(ISSN)","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"03014800"}]}]},"item_16_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00703822","subitem_source_identifier_type":"NCID"}]},"item_16_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"491.4","subitem_subject_scheme":"NDC"}]},"item_16_text_18":{"attribute_name":"形態","attribute_value_mlt":[{"subitem_text_value":"433390 bytes"}]},"item_16_text_47":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"雑誌掲載論文"}]},"item_16_text_48":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Journal Article"}]},"item_16_text_49":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_16_text_50":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"01"}]},"item_16_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Funakoshi, Yayoi"}],"nameIdentifiers":[{"nameIdentifier":"109343","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Omori, Hisamitsu"}],"nameIdentifiers":[{"nameIdentifier":"109344","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Katoh, Takahiko"}],"nameIdentifiers":[{"nameIdentifier":"109345","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-02"}],"displaytype":"detail","filename":"JNSV56_1_27-33.pdf","filesize":[{"value":"433.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JNSV56_1_27-33.pdf","url":"https://kumadai.repo.nii.ac.jp/record/24534/files/JNSV56_1_27-33.pdf"},"version_id":"9e47b18f-4af4-4597-9bdd-aad2d6da43c3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"bone mineral density","subitem_subject_scheme":"Other"},{"subitem_subject":"gene polymorphism","subitem_subject_scheme":"Other"},{"subitem_subject":"lifestyle factors","subitem_subject_scheme":"Other"},{"subitem_subject":"vitamin D receptor","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relation of Bone Mineral Density to Vitamin D Receptor Gene Polymorphism and Lifestyle Factors in Japanese Female Workers Aged 22-44 Years: A Cross-Sectional Study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relation of Bone Mineral Density to Vitamin D Receptor Gene Polymorphism and Lifestyle Factors in Japanese Female Workers Aged 22-44 Years: A Cross-Sectional Study"}]},"item_type_id":"16","owner":"1","path":["443"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-03-03"},"publish_date":"2011-03-03","publish_status":"0","recid":"24534","relation_version_is_last":true,"title":["Relation of Bone Mineral Density to Vitamin D Receptor Gene Polymorphism and Lifestyle Factors in Japanese Female Workers Aged 22-44 Years: A Cross-Sectional Study"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T18:23:58.293145+00:00"}