@article{oai:kumadai.repo.nii.ac.jp:00024711,
 author = {川浦, 一晃 and 三木, 理沙 and Miki, Risa and 島, 絵里子 and Shima, Eriko and 本田, 宗吉 and Honda, Sokichi and 副田, 二三夫 and 白崎, 哲哉 and Shirasaki, Tetsuya and 高濱, 和夫 and 川浦, 一晃 and Kawaura, Kazuaki and 三木, 理沙 and Miki, Risa and 島, 絵里子 and Shima, Eriko and 本田, 宗吉 and Honda, Sokichi and 副田, 二三夫 and Soeda, Fumio and 白崎, 哲哉 and Shirasaki, Tetsuya and 高濱, 和夫 and Takahama, Kazuo},
 issue = {3},
 journal = {Neuroscience Letters},
 month = {Sep},
 note = {application/pdf, 論文(Article), Recently, we reported that a centrally acting non-narcotic antitussive (cough suppressant drug),
tipepidine produces an antidepressant-like effect in the forced swimming test in rats. Because
pharmacological properties of tipepidine apparently differ from those of typical antidepressants
developed to date, we speculated that caramiphen, another centrally acting antitussive, has an
antidepressant-like effect. That effect of caramiphen was studied in rats using the forced swimming test. 
Caramiphen at 20 and 40 mg/kg i.p. significantly reduced immobility. At 40 mg /kg i.p., it increased
climbing behavior. Even at 40 mg /kg, this drug had no effect on locomotor activity. Results suggest
that a centrally acting antitussive possessing inhibition of GIRK channels has an antidepressant-like
effect., http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0G-50GWNCT-2&_user=4545557&_coverDate=09%2F13%2F2010&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_acct=C000008298&_version=1&_urlVersion=0&_userid=4545557&md5=cafaf36c8982e86ec114e03bb455f157&searchtype=a},
 pages = {188--190},
 title = {Antidepressant-like effect of centrally acting non-narcotic antitussive caramiphen in a forced swimming test},
 volume = {481},
 year = {2010},
 yomi = {ミキ, リサ and シマ, エリコ and ホンダ, ソウキチ and シラサキ, テツヤ and カワウラ, カズアキ and ミキ, リサ and シマ, エリコ and ホンダ, ソウキチ and ソエダ, フミオ and シラサキ, テツヤ and タカハマ, カズオ}
}