@article{oai:kumadai.repo.nii.ac.jp:00024728,
 author = {尾田, 済太郎 and 粟井, 和夫 and 船間, 芳憲 and 宇都宮, 大輔 and 彌永, 由美 and 河中, 功一 and 山下, 康行 and Oda, Seitaro and Awai, Kazuo and Funama, Yoshinori and 宇都宮, 大輔 and Utsunomiya, Daisuke and Yanaga, Yumi and Kawanaka, Koichi and 山下, 康行 and Yamashita, Yasuyuki},
 issue = {3},
 journal = {Japanese Journal of Radiology},
 month = {Apr},
 note = {application/pdf, 論文(Article), Purpose:  To investigate the detectability of simulated pulmonary nodules with different X-ray attenuation by flat-panel detector (FPD) chest radiography using a dual-exposure dual-energy subtraction (DES) technique.
Materials and Methods:  Using a FPD radiography system we obtained 108 sets of chest radiographs of a chest phantom.  They consisted of 54 sets each of chest radiographs with- and without simulated nodules.  Each data set contained a standard- and a corresponding dual-energy subtracted chest radiograph (DES image).  The diameter of the simulated nodules was 8-, 10-, and 12 mm; nodules of each size manifested attenuation of -450, -200, and 30 Hounsfield units (HU).  We performed receiver operating characteristic (ROC) analysis to compare the observers’ performance in detecting nodules.
Results:  For -450 HU nodules the mean area under the ROC curve (AUC) without and with DES images was 0.66 and 0.77, respectively; the difference was significant (paired t-test, p < 0.01).  For nodules with -200- and 30 HU, there was no significant difference in the AUC value (0.79 vs. 0.77, p=0.13; 0.92 vs. 0.94, p=0.17, respectively).
Conclusion:  The addition of DES images to standard chest radiographs improved the performance of radiologists charged with detecting simulated nodules with an attenuation of -450 HU., http://www.springerlink.com/content/kq88067j70104k40/},
 pages = {214--219},
 title = {Effects of dual-energy subtraction chest radiography on detection of small pulmonary nodules with varying attenuation: receiver operating characteristic analysis using a phantom study},
 volume = {28},
 year = {2010},
 yomi = {ウツノミヤ, ダイスケ and ヤマシタ, ヤスユキ}
}