@techreport{oai:kumadai.repo.nii.ac.jp:00024775, author = {友田, 明美 and Tomoda, Akemi and 友田, 明美}, month = {May}, note = {application/pdf, 研究報告書, 小児期の被虐待による脳発達に及ぼす影響として、被性的虐待の視覚野への影響、被暴言虐待の聴覚野への影響、被厳格体罰の前頭前野への影響、両親間のDV 目撃による視覚野への影響が高解像度MRI 解析で明らかになった。さらに年齢によって虐待ストレスの局所脳へ及ぼす影響が異なり、しかも様々な領域で時期が異なる感受性(臨界)期の存在を示唆する所見が得られた。小児期の虐待ストレスが、感覚系が活動的に働く領域に影響を及ぼしており、脳構成細胞である軸索・デンドライト・グリアを含めたネットワーク形成不全が起こっている可能性が示唆された。, Brain development is largely guided by genetic factors, but the final form is sculpted by environmental factors and early experience. Exposure to traumatic events such as childhood abuse and neglect, have been associated with alterations in the size or functional activity of a variety of brain regions. We have conducted a voxel-based morphometry (VBM) study in young adults with histories of exposure to repeated episodes of childhood sexual abuse and found that the most significant differences were bilateral reductions in gray matter volume (GMV) in the visual cortex (BA 17, 18). Similarly, we conducted a VBM analysis in young adults exposed to parental verbal aggression, and observed an increase in the left superior temporal gyrus (BA 22). These findings fit with an emerging hypothesis that exposure to early adversity may be associated with alterations in sensory systems that process and convey the adverse sensory experience. Severe abuse during childhood can cause abnormal brain development and have a negative impact later in life.}, title = {児童虐待の脳発達におよぼす影響と敏感期に関する研究}, year = {2010}, yomi = {トモダ, アケミ} }