{"created":"2023-06-19T09:12:55.836531+00:00","id":24852,"links":{},"metadata":{"_buckets":{"deposit":"59ab6a5c-a4b6-4c20-aa4d-d9914c8796d5"},"_deposit":{"created_by":127,"id":"24852","owners":[127],"pid":{"revision_id":0,"type":"depid","value":"24852"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00024852","sets":["343:344:345:346"]},"author_link":[],"item_14_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-02-17","bibliographicIssueDateType":"Issued"}}]},"item_14_date_granted_74":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2010-02-17"}]},"item_14_degree_grantor_72":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"熊本大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17401","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_14_degree_name_71":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_14_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"長時間作用型のカルシウム拮抗剤であるアゼルニジピンは、その高い脂溶性と血管壁選択性から脳血流量(cerebral blood flow: CBF)増加作用が期待されている。本研究の目的は、脳梗塞慢性期高血圧患者におけるアゼルニジピンの安全性、有用性、CBFに対する効果について、I-IMP single photon emission computed tomography (SPECT)を用いて評価することである。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"Azelnidipine, a long-acting calcium-channel blocker, is highly lipid soluble and selective for the vascular wall, and is expected to have an increasing effect on cerebral blood flow (CBF). The aim of this study is to investigate its safety and efficacy in stroke patients in the chronic stage as far as CBF is concerned using N-isopropyl-p-I-iodo amphetamine (I-IMP) single photon emission computed tomography (SPECT).","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_14_dissertation_number_75":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第930号"}]},"item_14_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本大学","subitem_publisher_language":"ja"}]},"item_14_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"377.5","subitem_subject_scheme":"NDC"}]},"item_14_text_81":{"attribute_name":"学位番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"乙博医第930号"}]},"item_14_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"渡邉, 聖樹","creatorNameLang":"ja"},{"creatorName":"ワタナベ, マサキ","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Masaki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-03-02"}],"displaytype":"detail","filename":"32-930.pdf","filesize":[{"value":"1.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"32-930.pdf","url":"https://kumadai.repo.nii.ac.jp/record/24852/files/32-930.pdf"},"version_id":"59722d5b-29fb-480f-b15f-ac47fe9dcf52"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"脳卒中","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"脳梗塞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"高血圧","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"CCB","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"アゼルニジピン","subitem_subject_language":"ja-Kana","subitem_subject_scheme":"Other"},{"subitem_subject":"SPECT","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"脳梗塞慢性期高血圧患者におけるアゼルニジピンの脳血流に対する効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"脳梗塞慢性期高血圧患者におけるアゼルニジピンの脳血流に対する効果","subitem_title_language":"ja"},{"subitem_title":"ノウコウソク マンセイキ コウケツアツ カンジャ ニ オケル アゼルニジピン ノ ノウ ケツリュウ ニ タイスル コウカ","subitem_title_language":"ja-Kana"},{"subitem_title":"Effect of Azelnidepine on cerebral blood flow in hypertensive patients with post ischemic stroke","subitem_title_language":"en"}]},"item_type_id":"14","owner":"127","path":["346"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-06-28"},"publish_date":"2011-06-28","publish_status":"0","recid":"24852","relation_version_is_last":true,"title":["脳梗塞慢性期高血圧患者におけるアゼルニジピンの脳血流に対する効果"],"weko_creator_id":"127","weko_shared_id":-1},"updated":"2026-02-25T01:48:29.401301+00:00"}