@article{oai:kumadai.repo.nii.ac.jp:00024912,
 author = {太田, 智子 and 太田, 和俊 and 城野, 博史 and 藤森, 裕巳 and 植田, 光晴 and 神力, 悟 and 末吉, 貴直 and 篠原, 正徳 and 安東, 由喜雄 and Ota, Tomoko and Ota, Kazutoshi and Jono, Hirofumi and Fujimori, Hiromi and 植田, 光晴 and Ueda, Mitsuharu and Shinriki, Satoru and Sueyoshi, Takanao and 安東, 由喜雄 and Ando, Yukio and Shinohara, Masanori},
 issue = {9},
 journal = {Oral Oncology},
 month = {Sep},
 note = {application/pdf, application/pdf, 論文(Article), The aims of this study were to investigate midkine (MK) expression patterns in salivary gland tumors (SGTs) and to evaluate the correlation between MK expression and the degree of malignancy. We performed immunohistochemistry to examine MK expression in specimens of adenoid cystic carcinoma (ACC), mucoepidermoid carcinoma (MEC), and pleomorphic adenoma (PA). In addition, we performed immunohistochemistry for CD31 and measured microvessel density (MVD), which is an indicator of angiogenesis. Immunohistochemistry showed that MK protein expression was significantly higher in specimens of malignant SGTs (ACC [P < 0.01] and MEC [P < 0.001]) than in benign SGT (PA) samples. Furthermore, MVD values tended to be higher in cases that exhibited high expression of MK, which indicated a significant correlation between the degree of MK expression and MVD (P < 0.001). These results suggest that MK may play important roles in malignant transformation and tumor angiogenesis in SGTs., http://www.sciencedirect.com/science/article/pii/S1368837510001879},
 pages = {657--661},
 title = {Midkine expression in malignant salivary gland tumors and its role in tumor angiogenesis},
 volume = {46},
 year = {2010},
 yomi = {ウエダ, ミツハル and アンドウ, ユキオ}
}