{"created":"2023-06-19T09:13:03.225306+00:00","id":24988,"links":{},"metadata":{"_buckets":{"deposit":"8602f377-8118-422f-b380-84835510d61c"},"_deposit":{"created_by":1,"id":"24988","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"24988"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00024988","sets":["413:443"]},"author_link":["113072","157974","113073"],"item_16_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-08-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"706","bibliographicPageStart":"694","bibliographicVolumeNumber":"86","bibliographic_titles":[{"bibliographic_title":"Proceedings of the Japan Academy Series B: Physical and Biological Sciences"}]}]},"item_16_creator_3":{"attribute_name":"別言語の著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"荒木, 淑郎","creatorNameLang":"ja"},{"creatorName":"アラキ, シュクロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Araki, Shukuro","creatorNameLang":"en"}],"familyNames":[{"familyName":"荒木","familyNameLang":"ja"},{"familyName":"アラキ","familyNameLang":"ja-Kana"},{"familyName":"Araki","familyNameLang":"en"}],"givenNames":[{"givenName":"淑郎","givenNameLang":"ja"},{"givenName":"シュクロウ","givenNameLang":"ja-Kana"},{"givenName":"Shukuro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"113072","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"安東, 由喜雄"}],"nameIdentifiers":[{"nameIdentifier":"113073","nameIdentifierScheme":"WEKO"}]}]},"item_16_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_16_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"論文(Article)","subitem_description_type":"Other"}]},"item_16_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"The authors reviewed contribution of Kumamoto University group to the progress of the studies on transthyretin (TTR)-related familial amyloidotic polyneuropathy (TTR-related FAP) for 42 years (from 1967 to 2009). Andrade (1952) first described a large group of patients with FAP in Portugal and Araki et al. (1967) in second discovered similar FAP patients in Arao, Kumamoto, Japan. Owing to progress in biochemical and molecular genetic analyses, FAP is now believed to occur worldwide. As of today, reports of about 100 different points of single or two mutations, or a deletion in the transthyretin (TTR) gene, have been published. The authors’ group has made pioneer works for study of FAP in the world. The focus on therapy in amylodosis will increase sharply as an impetus in near future, and successful treatments are expected.","subitem_description_type":"Other"}]},"item_16_description_77":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_description":"http://www.jstage.jst.go.jp/article/pjab/86/7/86_694/_article/-char/ja/","subitem_description_type":"Other"}]},"item_16_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japan 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