{"created":"2023-06-19T09:13:19.917441+00:00","id":25349,"links":{},"metadata":{"_buckets":{"deposit":"669b964f-b3ca-47b1-b463-c20f8a8dccda"},"_deposit":{"created_by":127,"id":"25349","owners":[127],"pid":{"revision_id":0,"type":"depid","value":"25349"},"status":"published"},"_oai":{"id":"oai:kumadai.repo.nii.ac.jp:00025349","sets":["343:344:345:346"]},"author_link":[],"item_14_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-02-22","bibliographicIssueDateType":"Issued"}}]},"item_14_date_granted_74":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2011-02-22"}]},"item_14_degree_grantor_72":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"熊本大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17401","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_14_degree_name_71":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_14_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"The hepatitis C virus (HCV) is one of the most important causes of chronic liver disease. This chronic infection induces chronic hepatitis, hepatic cirrhosis and hematoma. The cause of the liver carcinoma is thought to be a long series of inflammation. But even now, the mechanism is not completely clarified. Thus I tried to analyzed host factor that was upregulated by the persistence expression of HCV genome, and elucidate of oncogenic mechanism of HCV infection. The purpose of this study was finding of new approach to the HCV therapy.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_14_dissertation_number_75":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"乙第939号"}]},"item_14_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"熊本大学","subitem_publisher_language":"ja"}]},"item_14_subject_20":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"377.5","subitem_subject_scheme":"NDC"}]},"item_14_text_81":{"attribute_name":"学位番号","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"乙博医第939号"}]},"item_14_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"西村, 知裕","creatorNameLang":"ja"},{"creatorName":"ニシムラ, トモヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Nishimura, Tomohiro","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2020-03-02"}],"displaytype":"detail","filename":"32-0939.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"32-0939.pdf","url":"https://kumadai.repo.nii.ac.jp/record/25349/files/32-0939.pdf"},"version_id":"27c5fbb8-7b25-483e-8fc4-adf971a8c175"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HCV","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DHCR24","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"Clarification of the mechanism of p53 inactivation by the novel HCV infection-related protein 3β-hydroxysterol Δ24-reductase","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clarification of the mechanism of p53 inactivation by the novel HCV infection-related protein 3β-hydroxysterol Δ24-reductase","subitem_title_language":"en"},{"subitem_title":"新規HCV関連因子 3β-hydroxysterol Δ24-reductase によるp53 機能抑制機構の解明","subitem_title_language":"ja"},{"subitem_title":"シンキ HCV カンレン インシ 3β hydroxysterol Δ24 reductase ニ ヨル p53 キノウ ヨクセイ キコウ ノ カイメイ","subitem_title_language":"ja-Kana"}]},"item_type_id":"14","owner":"127","path":["346"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-10-07"},"publish_date":"2011-10-07","publish_status":"0","recid":"25349","relation_version_is_last":true,"title":["Clarification of the mechanism of p53 inactivation by the novel HCV infection-related protein 3β-hydroxysterol Δ24-reductase"],"weko_creator_id":"127","weko_shared_id":-1},"updated":"2026-02-25T01:48:39.544581+00:00"}