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Cognitive dysfunction correlates of mental fatigue induced in childhood chronic fatigue syndrome - A six-month follow-up study
http://hdl.handle.net/2298/24421
http://hdl.handle.net/2298/24421633d0d3d-cfb3-4dc4-b8ba-b8c2095acc94
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2012-05-08 | |||||
タイトル | ||||||
タイトル | Cognitive dysfunction correlates of mental fatigue induced in childhood chronic fatigue syndrome - A six-month follow-up study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | Modified advanced trail making test (mATMT), Childhood type chronic fatigue syndrome (CCFS), Cognitive function, Alternative attention | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
Kawatani, Junko
× Kawatani, Junko× Mizuno, Kei× Takano, Miyuki× Joudoi, Takako× Fukuda, Sanae× 友田, 明美 |
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別言語の著者 |
川谷, 淳子
× 川谷, 淳子× 水野, 敬× 高野, 美雪× 上土井, 貴子× 福田, 早苗× 友田, 明美 |
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内容記述 | ||||||
内容記述 | Objectives: The aim of this study was to investigate cognitive functions such as allocation and information processing in patients with childhood type chronic fatigue syndrome (CCFS) using modified advanced trail making test (mATMT). To examine cognitive function in chronic fatigue syndrome. The first aim of the present study was to test whether PCFS showed cognitive dysfunction. The second aim of the study was to cognitive function may be a reversible that can improve with therapy after 6 months, if PCFS showed cognitive dysfunction at baseline. Methods: 25 healthy children as controls and 19 patients with CCFS participated in this study. The subjects were 19 patients with chronic fatigue syndrome and 25 healthy controls(grades 7 to 9). Both patients and controls had (i) modified advanced trail making test (mATMT; ) which is computerized cognitive test (TaskA,B,C,D,E) and were instructed to indicate (ii) Chalder’s fatigue scale to evaluate their fatigue state using Chalder’s fatigue scale before and 6months after therapy).CCFS patients were assessed at follow-up(i,e. therapy ). Results: We calculated differences in reaction time as total reaction times on task A, B, C, or E subtracted by that on task D in the mATMT. The results indicate that 4 tasks from mATMT can discriminate CCFS patients from the control group by 70.5% accuracy. Especially, the average reaction time of the Task E contributes to the identification of CCFS. The amount of reaction time in TaskE improved and the amount of metal fatigues score and total fatigue score improved within the past 6 months are correlated. The improvement of their cognitive symptoms and improvement of set shifting function (??) correlated with an overall index of visual memory (r = .353, P = .032 and r= .448, P= .005). Conclusions: It shows that there is a relationship between improvement of cognitive symptoms caused by mental fatigue and improvement of set shifting function. Present findings indicate that |
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書誌情報 |
Brain and Development 巻 33, 号 10, p. 832-841, 発行年 2011-10 |
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ISSN | ||||||
収録物識別子 | 0387-7604 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 10.1016/j.braindev.2010.12.009 | |||||
権利 | ||||||
権利情報 | © 2011 Elsevier | |||||
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内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
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207410 bytes | ||||||
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出版タイプ | AM | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
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出版者 | Elsevier | |||||
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内容記述タイプ | Other | |||||
内容記述 | 論文(Article) | |||||
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雑誌掲載論文 | ||||||
資源タイプ・NII | ||||||
Journal Article | ||||||
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text | ||||||
資源タイプ・ローカル表示コード | ||||||
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URL | ||||||
内容記述タイプ | Other | |||||
内容記述 | http://www.sciencedirect.com/science/article/pii/S038776041000361X |