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Immunotherapy with pluripotent stem cell-derived dendritic cells
http://hdl.handle.net/2298/26641
http://hdl.handle.net/2298/266411d5a2bc0-ce6c-48f0-8cab-f54eba679012
| 名前 / ファイル | ライセンス | アクション |
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Figure 1.pdf (60.1 kB)
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Seminars in Immunopathology2011.VOL.33.pdf (98.0 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2013-01-29 | |||||
| タイトル | ||||||
| タイトル | Immunotherapy with pluripotent stem cell-derived dendritic cells | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Dendritic Cells, Embryonic Stem Cells, iPS Cells, Cell Therapy | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Senju, Satoru
× Senju, Satoru× Matsunaga, Yusuke× Fukushima, Satoshi× Hirata, Shinya× Motomura, Yutaka× 福間, 大喜× Matsuyoshi, Hidetake× 西村, 泰治 |
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| 別言語の著者 |
千住, 覚
× 千住, 覚× 松永, 雄亮× 福島, 聡× 平田, 真哉× 本村, 裕× 福間, 大喜× 松吉, 秀武× 西村, 泰治 |
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| 内容記述 | ||||||
| 内容記述 | In vivo transfer of dendritic cells (DC) has proven efficient in the priming of T cells, and is regarded as a powerful means of providing anti-cancer immunotherapy. Clinical trials of anti-cancer therapy with DC pulsed with peptide antigens have been carried out in many institutions, although dramatic therapeutic effect has not been observed in most of the trials. Negative regulation of the immune response by DC might be applicable to treatment of autoimmune diseases and transplantation medicine. Currently, the DC used for anti-cancer vaccine therapy are generated from the peripheral blood monocytes of the patients. However, there is a limitation in the number of available monocytes, and the potential of monocytes to differentiate into DC varies depending on the individual blood donors. To resolve the issue of the cell source for DC therapy, several groups have developed methods to generate DC from pluripotent stem cells. This review introduces methods to generate functional DC from pluripotent stem cells of mouse and human. | |||||
| 書誌情報 |
Seminars in Immunopathology 巻 33, 号 6, p. 603-612, 発行年 2011-11 |
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| ISSN | ||||||
| 収録物識別子 | 18632297 | |||||
| PubMed番号 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 21461992 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | 10.1007/s00281-011-0263-y | |||||
| 権利 | ||||||
| 権利情報 | © 2011 Springer Verlag | |||||
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| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
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| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
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| 98021 bytes | ||||||
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| 60116 bytes | ||||||
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| 出版タイプ | AM | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 491.8 | |||||
| 出版者 | ||||||
| 出版者 | Springer Verlag | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 雑誌掲載論文 | ||||||
| 資源タイプ・NII | ||||||
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| URL | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | http://link.springer.com/article/10.1007%2Fs00281-011-0263-y | |||||
