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Therapy-associated secondary tumor in patients with non-germinomatous malignant germ cell tumors
http://hdl.handle.net/2298/26601
http://hdl.handle.net/2298/26601d33b4d04-b14a-4c61-ba31-6b1ae04e2adb
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-01-29 | |||||
タイトル | ||||||
タイトル | Therapy-associated secondary tumor in patients with non-germinomatous malignant germ cell tumors | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | Non-germinomatous malignant germ cell tumor, Tumor marker, Radiotherapy, Chemotherapy | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
Nakamura, Hideo
× Nakamura, Hideo× Makino, Keishi× Ushio, Yukitaka× Arima, Ryoichi× Kuratsu, Jun-ichi |
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別言語の著者 |
中村, 英夫
× 中村, 英夫× 牧野, 敬史× 生塩, 之敬× 有馬, 良一× 倉津, 純一 |
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内容記述 | ||||||
内容記述 | We report 3 patients with non-germinomatous malignant germ cell tumor (NGMGCT) who developed therapy-associated secondary tumors. They were diagnosed as having NGMGCT by elevated serum levels of β-fetoprotein (AFP), human chorionic gonadotropin (HCG), or β-HCG. Preoperatively, all patients received a combination of etoposide and platinum-based chemotherapy and radiotherapy; neo-adjuvant therapy (NAT) was followed by complete excision of the residual tumor. Postoperatively, all underwent maintenance chemotherapy and all remained free of NGMGCT without recurrence. However, they developed therapy-associated secondary tumors, i.e. glioblastoma, meningioma, or cavernous angioma after an interval of 10.1-, 9.8-, and 8.2 years, respectively. The patient with gliobastoma died 1 year after its detection. The other 2 patients are currently alive; the meningioma was completely removed and the cavernous angioma is being monitored without additional treatment. To our knowledge, therapy-associated secondary tumors in patients treated for NGMGCT are rare. | |||||
書誌情報 |
Journal of Neuro-Oncology 巻 105, 号 2, p. 359-364, 発行年 2011-11 |
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ISSN | ||||||
収録物識別子 | 0167594X | |||||
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関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 21533838 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
関連識別子 | 10.1007/s11060-011-0597-2 | |||||
権利 | ||||||
権利情報 | © 2012 Springer | |||||
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内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
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内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
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内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
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内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
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著者版フラグ | ||||||
出版タイプ | AM | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 493 | |||||
出版者 | ||||||
出版者 | Springer | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | 論文(Article) | |||||
資源タイプ・ローカル | ||||||
雑誌掲載論文 | ||||||
資源タイプ・NII | ||||||
Journal Article | ||||||
資源タイプ・DCMI | ||||||
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資源タイプ・ローカル表示コード | ||||||
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URL | ||||||
内容記述タイプ | Other | |||||
内容記述 | http://link.springer.com/article/10.1007%2Fs11060-011-0597-2 |