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Protein phosphatases and their regulation in the control of mitosis
http://hdl.handle.net/2298/26381
http://hdl.handle.net/2298/263815ded225f-0974-4228-917a-6c4c07037fc6
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
EMBO Reports 2012 VOL13-3.pdf (810.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-01-16 | |||||
| タイトル | ||||||
| タイトル | Protein phosphatases and their regulation in the control of mitosis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | alpha-Endosulfine, CDK, Greatwall, mitosis, phosphatase | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Mochida, Satoru
× Mochida, Satoru× Hunt, Tim |
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| 別言語の著者 |
持田, 悟
× 持田, 悟 |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Cell cycle transitions depend on protein phosphorylation and dephosphorylation. The discovery of cyclin dependent kinases (CDKs) and their mode of activation by their cyclin partners explained many important aspects of cell cycle control. As the cell cycle is basically a series of recurrences of a defined set of events, protein phosphatases must obviously be as important as kinases. However, our knowledge about phosphatases lags well behind that of kinases. We still do not know exactly which phosphatase(s) is/are truly responsible for dephosphorylating CDK substrates, and we know very little about whether and how protein phosphatases are regulated. Here, we summarise our present understanding of the phosphatases that are important in the control of the cell cycle and pose the questions that need to be answered as regards the regulation of protein phosphatases. |
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| 書誌情報 |
EMBO Reports 巻 13, 号 3, p. 197-203, 発行年 2012-03 |
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| ISSN | ||||||
| 収録物識別子 | 1469221X | |||||
| PubMed番号 | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 22482124 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | 10.1038/embor.2011.263 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 値 | 810593 bytes | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 491 | |||||
| 出版者 | ||||||
| 出版者 | Nature Publishing Group | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 値 | 雑誌掲載論文 | |||||
| 資源タイプ・NII | ||||||
| 値 | Journal Article | |||||
| 資源タイプ・DCMI | ||||||
| 値 | text | |||||
| 資源タイプ・ローカル表示コード | ||||||
| 値 | 01 | |||||
| URL | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | http://www.nature.com/embor/journal/v13/n3/full/embor2011263a.html | |||||
