@article{oai:kumadai.repo.nii.ac.jp:00027313,
 author = {島田, 秀昭 and Shimada, Hideaki and 安武, 章 and 平島, 隆臣 and 高群, 泰隆 and 北野, 健 and Kitano, Takeshi and Waalkes, Michael P. and Waalkes, Michael P. and 島田, 秀昭 and Shimada, Hideaki and Yasutake, Akira and Hirashima, Takaomi and Takamure, Yasutaka and 北野, 健 and Kitano, Takeshi and Waalkes, Michael P. and Waalkes, Michael P. and 今村, 順茂 and Imamura, Yorishige},
 issue = {2},
 journal = {Toxicology in Vitro},
 month = {Mar},
 note = {application/pdf, application/pdf, application/pdf, application/pdf, application/pdf, 論文(Article), Strain difference in the accumulation of cadmium (Cd) by liver slices was examined in inbred Cd-resistant Wistar-Imamichi (WI) and Cd-sensitive Fischer 344 (F344) rats. The accumulation of Cd by liver slices of WI rats was significantly lower than that of F344 rats, suggesting strain-related differences in the transport of Cd into the liver cells of these two rat strains. In addition, a similar strain difference was observed in the accumulation of zinc (Zn) by liver slices from WI and F344 rats. Cd accumulation by F344 liver slices decreased when Zn was added to the medium in combination with Cd. Furthermore, in F344 liver slices, Zn accumulation was significantly decreased when Cd was added to the medium. These results suggest that the accumulation of Cd by the liver is probably mediated, at least in part, by Zn transport systems. However, we found no strain difference in hepatic ZnT3 or ZIP3 transcript levels between WI and F344 rats. Further work is in progress to identify the transporter that causes the strain differences in hepatic Cd accumulation seen with WI and F344 rats., http://www.sciencedirect.com/science/article/pii/S0887233307002597},
 pages = {338--343},
 title = {Strain difference of cadmium accumulation by liver slices of inbred Wistar-Imamichi and Fischer 344 rats},
 volume = {22},
 year = {2008},
 yomi = {シマダ, ヒデアキ and キタノ, タケシ and シマダ, ヒデアキ and キタノ, タケシ and イマムラ, ヨリシゲ}
}