@article{oai:kumadai.repo.nii.ac.jp:00027314,
 author = {今村, 順茂 and Imamura, Yorishige and 大田黒, 弥紗 and 島田, 秀昭 and Shimada, Hideaki and 今村, 順茂 and Imamura, Yorishige and Ohtaguro, Misa and 島田, 秀昭 and Shimada, Hideaki},
 issue = {1-2},
 journal = {Journal of Steroid Biochemistry & Molecular Biology},
 month = {Oct},
 note = {application/pdf, application/pdf, application/pdf, application/pdf, application/pdf, application/pdf, 論文(Article), The effects of flavonoids and quinones on NADPH- and NADH-dependent 20α-hydroxysteroid dehydrogenase (20α-HSD) activities were examined in cytosolic fractions from the liver and kidney of mice. Judging from the data for the inhibition of NADPH- and NADH-dependent 20α-HSD activities by flavonoids and quinones, enzyme catalyzing renal NADPH-dependent 20α-HSD activity was found to be distinct from enzyme(s) catalyzing hepatic NADPH- and NADH-dependent 20α-HSD activities. Sulfobromophthalein (SBP) had little ability to inhibit hepatic NADPH-dependent 20α-HSD activity and bromophenol blue (BPB) exhibited a weak activation against the enzyme activity, whereas SBP and BPB were potent and moderate inhibitors, respectively, of hepatic NADH-dependent 20α-HSD activity. Thus, enzyme catalyzing hepatic NADPH-dependent 20α-HSD activity appeared to be distinct from enzyme catalyzing hepatic NADH-dependent 20α-HSD activity. The data for the pH profiles of hepatic NADPH- and NADH-dependent 20α-HSD activities also led us to the conclusion. Based on these results, we propose the possibility that several distinct enzymes catalyze NADPH- and NADH-dependent 20α-HSD activities in cytosolic fractions from the liver and kidney of mice., http://www.sciencedirect.com/science/article/pii/S0960076007001549},
 pages = {120--126},
 title = {Several distinct enzymes catalyze 20α-hydroxysteroid dehydrogenase activity in mouse liver and kidney},
 volume = {107},
 year = {2007},
 yomi = {イマムラ, ヨリシゲ and シマダ, ヒデアキ and イマムラ, ヨリシゲ and シマダ, ヒデアキ}
}