@article{oai:kumadai.repo.nii.ac.jp:00028048, author = {増田, 稔郎 and 別府, 透 and 水元, 孝郎 and 石河, 隆敏 and 近本, 亮 and 林, 洋光 and Hayashi, Hiromitsu and 岡部, 弘尚 and 太田尾, 龍 and 哈, 斯塔 and Takamori, Hiroshi and 高森, 啓史 and 馬場, 秀夫 and 増田, 稔郎 and Masuda, Toshiro and Beppu, Toru and Mizumoto, Takao and Ishiko, Takatoshi and Chikamoto, Akira and 林, 洋光 and Hayashi, Hiromitsu and Okabe, Hirohisa and Otao, Ryu and Hasita, Horlad and Takamori, Hiroshi and Baba, Hideo}, issue = {115}, journal = {Hepato-Gastroenterology}, month = {May}, note = {application/pdf, application/pdf, application/pdf, 論文(Article), Background/Aims: To investigate the efficacy and the safety of a hybrid ablation combining a percutaneous and endoscopic approach for multinodular hepatocellular carcinomas. Methodology: Hybrid ablation consists of a percutaneous approach for deep-sited tumors and an endoscopic approach for superficial ones. Between January 1991 and December 2007, fourty-eight patients with 139 nodules were treated with the hybrid ablation. The perioperative clinical data and prognosis of the hybrid approach group were compared with 15 patients with superficial and deep-sited multinodular HCCs treated by the pure endoscopic ablation. Results: With regard to the deep-site of the liver tumors, the complete disappearance of tumor enhancement was observed in 76 of 77 tumors (98.7%) in the hybrid ablation group, and 15 of 18 tumors (83.3%) in the pure endoscopic ablation group (p = 0.02). The mean operation time (236.5 minutes), the mean amount of intraoperative bleeding (20.3g), the median days of postoperative hospital stay (14 days), major complication rates (10.4%), and the 5-year overall survival (42%) in the hybrid ablation group were similar to the pure endoscopic group. Conclusions: Hybrid ablation is a clinically useful treatment for multinodular hepatocellular carcinomas located in both superficial and deep-site of the liver}, pages = {836--839}, title = {Hybrid Ablation using Percutaneous and Edoscopic Approach for Multi-Nodular Hepatocellular Carcinomas}, volume = {59}, year = {2012}, yomi = {ハヤシ, ヒロミツ and タカモリ, ヒロシ and マスダ, トシロウ and ハヤシ, ヒロミツ} }