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Halichonic acid, a new rearranged bisabolene-type sesquiterpene from a marine sponge Halichondria sp.
http://hdl.handle.net/2298/00043535
http://hdl.handle.net/2298/0004353529b39589-5635-4a82-a811-d6f53c5b2f49
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
0040-4039v60_1079-1081 (435.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-04-12 | |||||
| タイトル | ||||||
| タイトル | Halichonic acid, a new rearranged bisabolene-type sesquiterpene from a marine sponge Halichondria sp. | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Marine sponge, Bisabolene-type sesquiterpene, Halichondria sp., ECD spectrum calculation | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Raiju, Kenta
× Raiju, Kenta× Hitora, Yuki× Kato, Hikaru× Ise, Yuji× Angkouw, Esther D.× Mangindaan, Remy E.P.× Tsukamoto, Sachiko |
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| 抄録 | ||||||
| 内容記述 | A new compound, halichonic acid (1), was isolated from a marine sponge Halichondria sp., together with (6R,7S)-7-amino-7,8-dihydro-α-bisabolene (2). The structure of 1 was elucidated by spectroscopic analysis and ECD spectrum calculation to be a rearranged bisabolene-type sesquiterpene having a 3-azabicyclo[3.3.1]nonene moiety. Compound 2 was cytotoxic against HeLa cells with an IC50 value of 50?μM, whereas 1 did not show cytotoxicity even at 50?μM. It is possible that 1 is biosynthesized from farnesyl pyrophosphate and glycine, with rearrangement. | |||||
| 書誌情報 |
en : Tetrahedron Letters 巻 60, 号 15, p. 1079-1081, 発行年 2019-04-11 |
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| ISSN | ||||||
| 収録物識別子 | 0040-4039 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | https://doi.org/10.1016/j.tetlet.2019.03.030 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2019 This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 483.2 | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 499.3 | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
