WEKO3
アイテム
Bioconversion of 6-epi-Notoamide T produces metabolites of unprecedented structures in a marine-derived Aspergillus sp.
http://hdl.handle.net/2298/00043552
http://hdl.handle.net/2298/00043552a648830a-f165-43c4-8557-99b552bcc364
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
0040-4039v56_247-251 (562.0 kB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2020-10-27 | |||||
| タイトル | ||||||
| タイトル | Bioconversion of 6-epi-Notoamide T produces metabolites of unprecedented structures in a marine-derived Aspergillus sp. | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題 | Notoamide, Aspergillus sp., Bioconversion, Alkaloid | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Kato, Hikaru
× Kato, Hikaru× Nakahara, Takashi× Yamaguchi, Michitaka× Kagiyama, Ippei× Finefield, Jennifer M.,× James D., Sunderhaus× Sherman, David H.× Robert M., Williams× Tsukamoto, Sachiko |
|||||
| 抄録 | ||||||
| 内容記述 | We previously described the bioconversion of Notoamide T into (+)-Stephacidin A and (−)-Notoamide B, which suggested that Versicolamide B (8) is biosynthesized from 6-epi-Notoamide T (10) via 6-epi-Stephacidin A. Here we report that [13C]2-10 was incorporated into isotopically enriched 8 and seven new metabolites, which were not produced under normal culture conditions. The results suggest that the addition of excess precursor activated the expression of dormant tailoring genes giving rise to these structurally unprecedented metabolites. | |||||
| 書誌情報 |
en : Tetrahedron Letters 巻 56, 号 1, p. 247-251, 発行年 2015-01-01 |
|||||
| ISSN | ||||||
| 収録物識別子 | 0040-4039 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | https://doi.org/10.1016/j.tetlet.2014.11.083 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2014 This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 474.73 | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 499.3 | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 言語 | en | |||||
