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Potential advantage of preoperative three-dimensional mapping of sentinel nodes in breast cancer by a hybrid single photon emission CT (SPECT)/CT system
http://hdl.handle.net/2298/16290
http://hdl.handle.net/2298/1629012511194-29b3-4fc1-a3f8-8752773d3f80
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
SO2010_19_2.pdf (495.3 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2010-10-08 | |||||
| タイトル | ||||||
| タイトル | Potential advantage of preoperative three-dimensional mapping of sentinel nodes in breast cancer by a hybrid single photon emission CT (SPECT)/CT system | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Sentinel Node Mapping, Breast cancer, 3D-SPECT/CT, metastases | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Ibusuki, Mutsuko
× Ibusuki, Mutsuko× 山本, 豊× Kawasoe, Teru× Shiraishi, Shinya× 冨口, 静二× 山下, 康行× 本田, 由美× Iyama, Kenichi× Iwase, Hirotaka |
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| 別言語の著者 |
指宿, 睦子
× 指宿, 睦子× 山本, 豊× 川添, 輝× 白石, 慎哉× 冨口, 静二× 山下, 康行× 本田, 由美× 猪山, 賢一× 岩瀬, 弘敬 |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Objective: This study aims to assess the role of three dimensional single-photon emission computed tomography (3D-SPECT/CT) in sentinel node (SN) identification, and to analyze the impact of such information on estimating metastases to SNs. nBackground: Nodal status is a key factor for breast cancer. SN biopsy has been established as the alternative to routine axillary dissection these days. We investigated both the anatomical location of SNs demonstrated by our 3D-SPECT/CT system and the correlation to SNpositivity. nMethods: Two hundred and twenty-three clinically node-negative patients underwent SN biopsy. All of the axillary structures, including SNs, were visualized by a SPECT/CTcombined system after subcutaneous injection of 99mTc-phytate. By plotting the visualized SNs, the most frequent SN location ‘Pedestal area (PA)’ was designated. nResults: SPECT/CT detected 99mTc uptake in 217 cases (97.3%). 3D-SPECT/CT images visualized the accurate location of SNs in each case. In patients whose SNs were histopathologically negative (SN-), 228 (98.3%) SNs were found in the PA, and 4 (1.7%) were in other zones. In those with histopathologically positive SNs (SN+), 65 (78.3%) SNs were in the PA and 18 (21.7%) were outside it. The difference in SN distribution (i.e., in or out of the PA) between SN+ and SN- patients was statistically significant (p<0.001, chi-square test). nConclusions: SN biopsy navigated by 3D-SPECT/CT can clarify the reoperative anatomical localization of SNs in patients with breast cancer. Atypical distribution of SNs out of the PA may suggest SN positivity, reflecting failure of the lymphatic drainage systems. | |||||
| 書誌情報 |
Surgical Oncology 巻 19, 号 2, p. 88-94, 発行年 2010-06 |
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| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | 10.1016/j.suronc.2009.04.001 | |||||
| 権利 | ||||||
| 権利情報 | Copyright © 2010 Elsevier Ltd. All rights reserved | |||||
| 情報源(ISSN) | ||||||
| 関連名称 | 09607404 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 値 | 495317 bytes | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 494 | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 値 | 雑誌掲載論文 | |||||
| 資源タイプ・NII | ||||||
| 値 | Journal Article | |||||
| 資源タイプ・DCMI | ||||||
| 値 | text | |||||
| 資源タイプ・ローカル表示コード | ||||||
| 値 | 01 | |||||
