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Identification of four sumo paralogs in the medaka fish, oryzias latipes, and their classification into two subfamilies
http://hdl.handle.net/2298/22281
http://hdl.handle.net/2298/22281165eb19d-1c64-4386-8229-1ff3fd178502
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
BG2010_48_9-10r.pdf (1.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2011-11-18 | |||||
| タイトル | ||||||
| タイトル | Identification of four sumo paralogs in the medaka fish, oryzias latipes, and their classification into two subfamilies | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題 | Post-translational modification, Small ubiquitin-related modifier (SUMO), Medaka fish | |||||
| 資源タイプ | ||||||
| 資源タイプ | journal article | |||||
| 著者 |
Seki, Daisuke
× Seki, Daisuke× Obata, Shinpei× Shirozu, Tsuyoshi× 北野, 健× 斉藤, 寿仁 |
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| 別言語の著者 |
関, 大亮
× 関, 大亮× 小幡, 晋平× 白水, 剛× 北野, 健× 斉藤, 寿仁 |
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| 内容記述 | ||||||
| 内容記述 | At least four paralogs of the small ubiquitin-related modifier (SUMO) exist in humans, but there is limited information about SUMO paralogs from other vertebrate species. We isolated the four cDNA encoding proteins, similar to human SUMOs, from the medaka fish, Oryzias latipes: OlSUMO-1, OlSUMO-2, OlSUMO-3, and OlSUMO-4. The amino acid sequences of OlSUMO-2, OlSUMO-3 and OlSUMO-4 are 89‒94% identical, but they share only 45% identity with OlSUMO-1. Phylogenetic analysis, transient expression of OlSUMOs in cultured cells and in vitro binding of OlSUMOs with two different SUMO-interacting proteins demonstrated that the medaka SUMO paralogs can be grouped into two subfamilies, OlSUMO-1 and OlSUMO-2/3/4, respectively. Furthermore, this is the first report of all four OlSUMO transcripts being expressed in medaka embryos, implying that they have a role in fish development. The study will improve understanding of the relationship between structural and functional diversity of SUMO paralogs during vertebrate evolution. | |||||
| 書誌情報 |
Biochemical Genetics 巻 48, 号 9-10, p. 737-750, 発行年 2010-10 |
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| ISSN | ||||||
| 収録物識別子 | 00062928 | |||||
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| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00564420 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 関連識別子 | 10.1007/s10528-010-9356-x | |||||
| 権利 | ||||||
| 権利情報 | ©Springer Science+Business Media, LLC 2010 | |||||
| 情報源(ISSN) | ||||||
| 関連名称 | 00062928 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 形態 | ||||||
| 1347461 bytes | ||||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 463 | |||||
| 出版者 | ||||||
| 出版者 | springer | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 論文(Article) | |||||
| 資源タイプ・ローカル | ||||||
| 雑誌掲載論文 | ||||||
| 資源タイプ・NII | ||||||
| Journal Article | ||||||
| 資源タイプ・DCMI | ||||||
| text | ||||||
| 資源タイプ・ローカル表示コード | ||||||
| 01 | ||||||
| URL | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | http://www.springerlink.com/content/p7h80l28340t5271/ | |||||
