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Genome Diversification Mechanism of Rodent and Lagomorpha Chemokine Genes
http://hdl.handle.net/2298/28461
http://hdl.handle.net/2298/28461e66f4b54-c0e5-4c9f-8341-f3ff6d6daf92
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出版社版 (568.3 kB)
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Phylogenetic_tree.pdf (71.3 kB)
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ChemokineDomainFASTA.pdf (34.0 kB)
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ChemokineFASTA.pdf (56.2 kB)
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| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-03-11 | |||||
| タイトル | ||||||
| タイトル | Genome Diversification Mechanism of Rodent and Lagomorpha Chemokine Genes | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ | conference object | |||||
| 著者 |
Shibata, Kanako
× Shibata, Kanako× Nomiyama, Hisayuki× Yoshie, Osamu× Tanase, Sumio |
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| 別言語の著者 |
柴田, 佳菜子
× 柴田, 佳菜子× 野見山, 尚之× 義江, 修× 棚瀬, 純男 |
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| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Chemokines are a large family of small cytokines that are involved in host defence and body homeostasis through recruitment of cells expressing their receptors. Their genes are known to undergo rapid evolution. Therefore, the number and content of chemokine genes can be quite diverse among the different species, making the orthologous relationships often ambiguous even between closely related species. Given that rodents and rabbit are useful experimental models in medicine and drug development, we have deduced the chemokine genes from the genome sequences of several rodent species and rabbit and compared them with those of human and mouse to determine the orthologous relationships. The interspecies differences should be taken into consideration when experimental results from animal models are extrapolated into humans. The chemokine gene lists and their orthologous relationships presented here will be useful for studies using these animal models. Our analysis also enables us to reconstruct possible gene duplication processes that generated the different sets of chemokine genes in these species. | |||||
| 書誌情報 |
BioMed Research International 巻 2013, 号 856265, 発行日 2013 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 23146133 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1155/2013/856265 | |||||
| フォーマット | ||||||
| 内容記述 | application/pdf, application/pdf, application/pdf, application/pdf, application/pdf, application/pdf, application/pdf | |||||
| 形態 | ||||||
| 56247 bytes, 34021 bytes, 71329 bytes, 568306 bytes, 58238 bytes, 58238 bytes, 58238 bytes | ||||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 467.3 | |||||
| 出版者 | ||||||
| 出版者 | Hindawi Publishing Corporation | |||||
| 資源タイプ | ||||||
| 内容記述 | 発表資料 | |||||
| 資源タイプ・ローカル | ||||||
| 発表資料 | ||||||
| 資源タイプ・NII | ||||||
| Presentation | ||||||
| 資源タイプ・DCMI | ||||||
| text | ||||||
| 資源タイプ・ローカル表示コード | ||||||
| 05 | ||||||
| URI | ||||||
| http://hdl.handle.net/2298/28461 | ||||||
| URL | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | http://dx.doi.org/10.1155/2013/856265 | |||||
| コメント | ||||||
| 出版社版、および雑誌投稿論文（アクセプト前）のSupplementary Informationを掲載しています。 | ||||||
